Cellular immunity :the mechanism of acquired immunity characterized by the dominant role of T cell lymphocytes, also involves the activation of Macrophage cells and

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Ag Recognized by T Cell

• TCR recognize both MHC and antigenic peptides
• Co-binding with CD4 and CD8，the sensitivity↑ ~100 folds
• The MHC Molecules Bind Antigenic Peptides

T cells activation

• Two signals will initiate T cell activation The activated T cell will: – Producing cytokines – Expressing Cytokine receptors – proliferation – Differentiated – Expressing CD40L, Fasl
• Activation of T cell
• Activation of Tc