landscape

stem cell fate decision

discovery of RNA silencing

a classical miRNA biogenesis pathway

miRNAs and embryonic development

没有miRNA，无法进行着床，能复制

Global miRNA dosage control during development

miRNA 组织表达特异性

茎环的敲除- - →相分离- - →miRNA表达量下调- - →细胞内脂代谢抑制

GW9662- - -脂代谢抑制剂