1. What is the difference between linear and conformation epitope? Which of them can be recognized by its special antibody?
2. What is the difference between complete Ag and hapten? Small organic compounds usually are hapten, but some time severe immune response will happen if you contact with them, such as resin of True Lacquertree (漆树树脂，生漆）, how did these hapten change to complete antigen?

Introduction介绍

• Properties of antigen抗原的性质
• Antigen initiates Immunoresponse免疫应答的引发

Factors influencing Immunogenicity免疫原性的影响因素

• 1). Foreignness异物性
• 2). Epitope 抗原决定基
• 3). Physical and chemical factors
• 4). Biological system
• 5). administration给药

Type of antigen抗原的种类

• 1. Thymus胸腺 independent Ag
• 2. . Thymus dependent Ag胸腺依赖抗原
• Superantigen超抗原

The difference between normal Ag and superantigen