小鼠原肠作用时期细胞谱系发生(E6.0-E8.0)
灵长类原肠作用时期细胞谱系发生(E14-E21)
The aims of Developmental Biology: To study how multicellular organisms develop from a single cell -the fertilized egg, or zygote to an adult body and how zygotes are produced by an adult body.
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🍇 外胚层形成表皮和神经组织,内胚层形成肠腔上皮和消化腺上皮,中胚层形成骨骼、肌肉、血液、淋巴和其他结缔组织 - “内消呼肝胰,外表感神经
” 其他都是由中胚层发育而来的。
The Atlas of Mouse Development,小鼠发育图谱 (tsinghua.edu.cn)
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<aside> ⛈️ Study Resource
ninja nerd science
[email protected];NINJA_NERD123Osmosis
Gastrulation: From Embryonic Pattern to Form
Gradients and Tissue Patterning
<aside> ⛈️ Embryology 胚胎学 (unsw.edu.au)
1- reproductive system : fertilization
2- fertilization, cleavage, blastulation
7- development of the placenta
8- neurulation, vesiculation, neural crest cell migration
9- development of skeletal system
10- Development of the Heart .pdf
11- Development & Embryology of the GI Tract_ Part 1.pdf
111 - Development & Embryology of the GI Tract~ Part 2.pdf
12 - Development of the Respiratory System.pdf
13 - Development of the Urinary System.pdf
14 - Development of Reproductive System.pdf
15 - Development of Fetal Circulation.pdf
16 - Development of Vascular System.pdf
17 - Development of Pharyngeal Apparatus.pdf
[283 - Immunology Physiology] Immune System_ Overview.pdf](https://s3-us-west-2.amazonaws.com/secure.notion-static.com/62aa6ebf-ced2-409c-b4e3-d8d8c61ad09f/283_-_Immunology_Physiology_Immune_System__Overview.pdf)
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A roadmap for the Human Developmental Cell Atlas
https://embryology.med.unsw.edu.au/embryology/index.php/Mouse_Timeline_Detailed
Germinal stage
: involves several different processes that change an egg and sperm first into a zygote, and then into an embryo. The processes include fertilization, cleavage, blastulation, and implantation.embryo
: stage of growth and development that occurs from implantation in the uterus through the eighth week after fertilization【至少要要着床后才算胚胎】Carnegie stages
: In embryology, Carnegie stages are a standardized system of 23 stages used to provide a unified developmental chronology of the vertebrate embryo.Theiler stages
: Each Theiler stage is identified with one 'average' age, and a range of variation of real ages, centering on this average, that can be seen when real developing embryos are studied.first, second, third terimester
: A pregnancy is divided into trimesters: the first trimester is from week 1 to the end of week 12. the second trimester is from week 13 to the end of week 26. the third trimester is from week 27 to the end of the pregnancy. 怀孕的三个阶段,每个阶段都有代表性的特征。
The single-cell transcriptional landscape of mammalian organogenesis
Mice develop quickly, with just 21 days between fertilization and birth. The implantation of the blastocyst on
embryonic day (E) 4.0
is followed by gastrulation and the formation of germ layers onE6.5–E7.5
. At the early-somite stages, the embryo transits from gastrulation to early organogenesis, forming the neural plate and heart tube(E8.0–E8.5)
. In the ensuing days(E9.5–E13.5)
, the embryo expands from hundreds-of-thousands to over ten million cells, and concurrently develops nearly all major organ systems. Unsurprisingly, these four days have been intensively studied. Indeed, most genes that underlie major developmental defects can be studied in this window.